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Malic acid, an organic dicarboxylic acid with two stereoisomeric forms, plays an important biochemical role in both the Calvin cycle and the citric acid cycle. It is used as a food additive and preservative, a therapeutic agent, and a dietary supplement.
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Malate dehydrogenase (EC 1.1.1.37) (MDH) is an enzyme that catalyzes the mutual conversion of oxaloacetate and malate. It is associated with the oxidation/reduction of dinucleotide coenzymes.
Optimum pH 7.5-8.0
Optimum temperature 60°C
pH stability 3.0-9.0 (37°C, 30 minutes)
Thermal stability below 65°C (pH 7.5, 30 minutes)
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Malic acid disodium salt is the disodium salt of malic acid (sodium DL-malate) supplied as a high-purity biochemical reagent. It is commonly used as a buffering agent, pH regulator, and reagent in biochemical assays and food additive research.
High purity (98.0%) for reliable experimental results.
Useful as a buffering agent in aqueous solutions.
Suitable for biochemical assay and buffer preparation.
White crystalline powder, easy to weigh and handle.
Molecular formula C4H4Na2O5; molecular weight 178.05.
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The racemate of L-malic acid; reduces IFN-γ and TNF-α-induced CCL2 and ICAM expression in HaCaT human keratinocytes at 1 mM; inhibits epidermis and dermis thickening, as well as mast cell and eosinophil dermal infiltration in a mouse model of DNBC-induced atopic dermatitis at 10 mM
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Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities Malic acid plays a role in many sour or tangy foods Malic acid is an intermediate in the citric acid cycle[1][2]
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D-(+)-Malic acid is an active enantiomer of Malic acid and a competitive inhibitor of L-(-)malic acid transport. It is a human endogenous metabolite. It is a solid with a white to off-white appearance.
Used as a competitive inhibitor of L-(-)malic acid transport
Can be produced by certain bacteria from maleic acid
Suitable for various biological activities and research applications
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D-(+)-Malic acid, also known as D-Malic acid, is an active enantiomer of Malic acid. It functions as a competitive inhibitor of L-(-)-malic acid transport. It is utilized in research and analytical applications.
Active enantiomer of malic acid.
Functions as a competitive inhibitor of L-(-)-malic acid transport.
Suitable for research and analytical applications.
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